Poster Session No. 2 - Bioanalysis, Analysis & Quantitation of Small Molecules
00- Development and validation of an LC-MS/MS method for farnesol quantitation in Candida albicans biofilms
Marie-Claude Denis; Karine Venne; Annie Leduc; Jean Barbeau; Alexandra Furtos
Universite de Montreal, Montreal, Canada
00- Laser Diode Thermal Desorption (LDTD) Mass Spectrometry For High Throughput Analysis of Discovery DMPK in vitro and in vivo samples
The-Minh Tu1, Marie Roumi1, Alex Birsan1, Pierre Picard3, Jean Lacoursiere3, Markus Walles1 and Julie Ducharme1,2.
1AstraZeneca R&D Montreal, Canada; 2Faculté de Pharmacie, Université de Montréal; 3Phytronix Technologies
00- Validation of Pioglitazone in Human Serum by Two Sample - Introduction Methods: LDTD-APCI/MS/MS and LC-ESI/MS/MS
Michael Pugh, Don Gray, Rachel Sun, Brian J. Engel
BASi, 2701 Kent Avenue, West Lafayette, IN 47906
00- Coupling LC-fluorescence with tandem mass spectrometry for identifying modified amino acids
Andre LeBlanc; Boris Guichard; William Maupillier; Lekha Sleno
UQAM, Montreal, Canada
00- Development of an LC-MS/MS Method for Measurement of Deuterium Incorporation into DNA
Jin Wu1; Randall Purves1; Martine Lamarche1; Diane Ethier1; Yves Boie1; Mark P. Keller2; Mary E. Rabaglia2; Alan D. Attie2; Denis Normandin1; Simon Wong1; Kevin P. Bateman1
1Merck Frosst Canada, Kirkland, Canada; 2University of Wisconsin-Madison, Madison, WI
00- Quantitation of several HIV antiretroviral drugs in human plasma by LC tandem MS
David W. Blank; Brian J. Gilfix; Marcos DiFalco; Line Roy; Bernard F. Gibb
McGill University, Montreal , Canada
00- Monitoring the biodistribution and bioactivity of anticancer drugs by MRM-ESI Mass spectrometry
Qiyu Qiu; Anne-Laure Larroque; Marcos DiFalco; Line Roy; Bertrand J. Jean-Claude; Bernard F. Gibbs
McGill University, Montreal , Canada
00- Identifying and Quantifying Isoforms and Homologues
Johannes PC Vissers1; Richard R Sprenger2; Lennart Martens3; Scott Geromanos1; Jim Langridge1
1Waters Corporation, Manchester , United Kingdom ; 2Department of Medical Biochemistry, AMC, Amsterdam, Netherlands; 3EMBL European Bioinformatics Institute, Hinxton, United Kingdom
00- The Simultaneous Detection of Metabolites and Quantification of Drug Molecules in Bioanalytical Assays
Rob Plumb1; Paul Rainville1; Joanne Mather2; Ian Wilson3
1Waters, Milford , MA; 2waters corporation, Milford, MA; 3Astra Zeneca, Macderfield, UNITED KINGDOM
00- Evaluation of QTOF technology for the Quantitation of Drugs in Plasma
Julie Marr1; Walter Korfmacher2; Fangbiao Li2; Yunsheng Hsieh2; Bob Walker1; Jim Lau1
1Agilent Technologies, Mississauga , Canada ; 2Schering-Plough, Kenilworth, NJ
00- Application of High pH Mobile Phase in LC-ESI(+)/MS/MS Under HILIC Mode to Reach Optimal Sensitivity for Bioanalysis
Eugenie-Raphaelle Berube; Jean-Nicholas Mess; Milton Furtado; Fabio Garofolo
Algorithme Pharma Inc., Laval (Montreal), Quebec , CANADA
00- Successful Applications of Autosampler Needle Seat Back-flush to Reduce Carryover Using Common HPLC Hardware When Standard Washing Procedures Are Ineffective
Marie-Pierre Taillon; Nikolay Youhnovski; Simon Robert; Louis-Philippe Morin; Milton Furtado; Fabio Garofolo
Algorithme Pharma Inc., Laval (Montreal), Quebec , CANADA
00- Rapid analysis of metanephrines in biological fluids by automated online solid-phase extraction LC/MS/MS
Sylvie Beaudet1; Martin Sibum2; Luce Boulanger3
1MDS Analytical Technologies, Concord , Canada ; 2Spark Holland Inc.,, Emmen, NETHERLANDS; 3CHUM St-Luc Hospital, Montreal, Canada
00- Development of Enantiomeric LC-MS Analysis of Clenbuterol Doping Agent for Plasma Samples
Daniel Shollenberger, Craig R. Aurand, Carmen Santasania, David S. Bell, J.T. Lee
Supelco/Sigma-Aldrich, 595 N. Harrison Road, Bellefonte, PA 16823
00- FAIMS for drug discovery and development using an ion trap and a triple quadrupole MS
Keeley Murphy; Kevin Cook; Julie Horner; James Kapron; Nicholas Duczak, Jr; Mark Harrison
Thermo Fisher Scientific, San Jose, CA
00- Increasing the selectivity of clenbuterol detection in urine samples by using MS3 on a hybrid quadrupole-linear ion trap
Mauro Aiello; Rolf Kern; Beth Fernandez; Loren Olson
Applied Biosystems, San Jose , CA
00- Analysis of Impurities in Temocapril Using Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry
Ying Wang
Agilent Technologies (China), Shanghai , China
